The key matchup here is Antoine Griezmann's creativity against Tottenham's sometimes-shaky midfield screen. Atlético has been grinding out results in La Liga, recently taking down Real Betis 2-1 with a late Griezmann winner. Tottenham, meanwhile, just beat Brighton 3-1 but still looks vulnerable on the road in Europe. Expect a cagey affair, but Atlético's home advantage and defensive discipline will be too much. Atlético Madrid wins 1-0.
Predictions are for entertainment purposes only. Not gambling advice.